Description

4-Chloro-7-Hydroxy-Quinoline-3-Carbonitrile is a high-value, multi-functional quinoline derivative serving as a critical synthetic intermediate. Its unique halogenated and nitrile-substituted quinoline core makes it an essential building block for constructing complex molecular architectures in advanced research and development. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Versatile scaffold for further functionalization via reactions at the chloro, hydroxy, and nitrile groups.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	4-Chloro-7-Hydroxy-Quinoline-3-Carbonitrile
CAS No.	1017788-66-7
Molecular Formula	C10H5ClN2O
Molecular Weight	204.61 g/mol
Synonyms	7-Hydroxy-4-chloroquinoline-3-carbonitrile; 4-Chloro-7-hydroxyquinoline-3-carbonitrile; 3-Cyano-4-chloro-7-hydroxyquinoline; 1017788-66-7; 4-Chloro-7-quinolinol-3-carbonitrile; 7-Hydroxy-4-chloro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Hydroxy-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.