Description

8-Bromo-4-Chloro-7-Fluoro-Quinoline-3-Carbonitrile is a high-value, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular scaffold, featuring bromo, chloro, and fluoro substituents, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in oncology, antiviral, and CNS therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and advanced polymers with specific electronic properties.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis: Essential starting material for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis.

Basic Information

Product Name	8-Bromo-4-Chloro-7-Fluoro-Quinoline-3-Carbonitrile
CAS No.	1017788-60-1
Molecular Formula	C10H3BrClFN2
Molecular Weight	285.50 g/mol
Synonyms	8-Bromo-4-chloro-7-fluoroquinoline-3-carbonitrile; 3-Cyano-8-bromo-4-chloro-7-fluoroquinoline; 1017788-60-1; 8-Bromo-4-chloro-7-fluoro-3-quinolinecarbonitrile; 7-Fluoro-8-bromo-4-chloro-quinoline-3-carbonitrile; BCFQ-CN; 4-Chloro-8-bromo-7-fluoroquinoline-3-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-4-Chloro-7-Fluoro-Quinoline-3-Carbonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA). Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.