Description

3-Ethoxy-2,4-difluorocinnamic acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the ethoxy and difluoro substitution pattern, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting specific enzyme pathways where fluorination enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluorocinnamate structure contributes to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic semiconductors and liquid crystal compounds for display technologies.
• Chemical Research & Development: A versatile reagent for organic synthesis, used in cross-coupling reactions, cyclizations, and as a scaffold for creating complex molecular libraries.
• Fluorine Chemistry Studies: Valuable reference compound for investigating the effects of specific fluorine substitution patterns on chemical reactivity and physical properties.

Basic Information

Item	Details
Product Name	3-Ethoxy-2,4-Difluorocinnamic Acid
CAS No.	1017778-44-7
Molecular Formula	C₁₁H₁₀F₂O₃
Molecular Weight	228.19 g/mol
Synonyms	(E)-3-(3-Ethoxy-2,4-difluorophenyl)acrylic acid; 3-Ethoxy-2,4-difluorocinnamic acid; 2,4-Difluoro-3-ethoxycinnamic acid; (2E)-3-(3-Ethoxy-2,4-difluorophenyl)prop-2-enoic acid; 1017778-44-7; 3-Ethoxy-2,4-difluorocinammic acid
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2,4-difluorocinnamic acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.