Description

1-(2-Chloro-7-Fluoroquinolin-3-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate belonging to the quinoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting infectious diseases and other therapeutic areas. It is primarily needed by R&D laboratories, contract manufacturing organizations (CMOs), and pharmaceutical companies engaged in the development and production of novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel fluoroquinolone antibiotics and other quinoline-based therapeutic agents.
• Organic Synthesis Building Block: Used in research and development for constructing complex molecular architectures, leveraging its reactive carbonyl and halogenated quinoline core.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents and pesticides, where the quinoline scaffold is explored for bioactivity.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-(2-Chloro-7-Fluoroquinolin-3-Yl)Ethanone
CAS No.	1017463-76-1
Molecular Formula	C11H7ClFNO
Molecular Weight	223.63 g/mol
Synonyms	2-Chloro-7-fluoro-3-acetylquinoline; 3-Acetyl-2-chloro-7-fluoroquinoline; 1-(2-Chloro-7-fluoro-3-quinolyl)ethanone; Ethanone, 1-(2-chloro-7-fluoro-3-quinolinyl)-; 2-Chloro-7-fluoroquinoline-3-carbaldehyde (common misnomer, related compound); 1017463-76-1
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-7-Fluoroquinolin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.