Description

[4-(3-Chlorophenyl)Tetrahydro-2H-Pyran-4-Yl]Methylamine is a high-purity, synthetically versatile chiral amine building block. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly for creating novel active pharmaceutical ingredients (APIs) with complex stereochemistry. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel central nervous system (CNS) agents, receptor modulators, and other bioactive molecules.
• Agrochemical Development: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with specific stereochemical activity.
• Ligand and Catalyst Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and R&D: A valuable compound for methodological studies in organic synthesis and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	[4-(3-Chlorophenyl)Tetrahydro-2H-Pyran-4-Yl]Methylamine
CAS No.	1017450-92-8
Molecular Formula	C12H16ClNO
Molecular Weight	225.72 g/mol
Synonyms	1-[(4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-yl)]methanamine; (4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-yl)methanamine; 4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-ylmethylamine; 1-(4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-yl)methanamine; 4-(3-Chlorophenyl)-4-(aminomethyl)tetrahydro-2H-pyran; (4-(3-Chlorophenyl)tetrahydropyran-4-yl)methanamine
EINECS	Contact for details

Quality Control

Our [4-(3-Chlorophenyl)Tetrahydro-2H-Pyran-4-Yl]Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.