Description

2-Chloro-8-Methoxyquinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules and functional materials. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active quinoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science: Acts as a building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce complex functionalities.
• Dye & Pigment Industry: Functions as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Academic & R&D: A valuable reagent for methodological studies and exploring new chemical transformations in heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-8-Methoxyquinoline-3-Carbonitrile
CAS No.	1017329-32-6
Molecular Formula	C₁₁H₇ClN₂O
Molecular Weight	218.64 g/mol
Synonyms	8-Methoxy-2-chloroquinoline-3-carbonitrile; 2-Chloro-8-methoxy-3-quinolinecarbonitrile; 3-Cyano-2-chloro-8-methoxyquinoline; Quinoline-3-carbonitrile, 2-chloro-8-methoxy-; 1017329-32-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-8-Methoxyquinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.