Description

2-Chloro-6-Fluoroquinoline-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated quinoline scaffold enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel quinolone and fluoroquinolone antibiotic candidates and other bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for enhanced efficacy.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, including amide coupling and nucleophilic substitution reactions.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and advanced polymers.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	2-Chloro-6-Fluoroquinoline-3-Carboxylic Acid
CAS No.	1017222-23-9
Molecular Formula	C10H5ClFNO2
Molecular Weight	225.60 g/mol
Synonyms	2-Chloro-6-fluoroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 2-chloro-6-fluoro-; 1017222-23-9; 2-Chloro-6-fluoro-quinoline-3-carboxylic acid; 2-Chloro-6-fluoro-3-quinolinecarboxylic acid; 6-Fluoro-2-chloroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.