Description

2-Chloro-7-Fluoroquinoline-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its unique molecular scaffold, featuring both chloro and fluoro substituents, makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone and fluoroquinolone-based antibiotics and other therapeutic agents.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and material chemistry.
• Material Science Applications: Potential use in the development of organic electronic materials, ligands for catalysis, and fluorescent dyes.
• Academic & R&D: Essential for research in organic synthesis methodologies and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Chloro-7-Fluoroquinoline-3-Carboxylic Acid
CAS No.	1017157-81-1
Molecular Formula	C₁₀H₅ClFNO₂
Molecular Weight	225.60 g/mol
Synonyms	2-Chloro-7-fluoroquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 2-chloro-7-fluoro-; 2-Chloro-7-fluoro-3-quinolinecarboxylic acid; 1017157-81-1; 2-Chloro-7-fluoro-quinoline-3-carboxylic acid; 2-Chloro-7-fluoro-3-carboxyquinoline; 7-Fluoro-2-chloroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Fluoroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and consistent supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.