Description

5-Chloro-3-Ethyl-2-Hydrazino-8-Methylquinoline Hydrochloride is a specialized quinoline derivative with a reactive hydrazino group, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the construction of complex heterocyclic frameworks, particularly for pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, including fungicides and herbicides, leveraging the quinoline scaffold's bioactivity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules used in materials science, dyes, and specialty chemicals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Fundamental reagent for method development and novel heterocycle synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Chloro-3-Ethyl-2-Hydrazino-8-Methylquinoline Hydrochloride
CAS No.	1017116-92-5
Molecular Formula	C₁₃H₁₇Cl₂N₃
Molecular Weight	286.20 g/mol
Synonyms	5-Chloro-3-ethyl-2-hydrazinyl-8-methylquinoline hydrochloride; 2-Hydrazino-5-chloro-3-ethyl-8-methylquinoline hydrochloride; 8-Methyl-5-chloro-3-ethyl-2-hydrazinoquinoline HCl; Quinoline, 5-chloro-3-ethyl-2-hydrazino-8-methyl-, hydrochloride; CAS 1017116-92-5
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Ethyl-2-Hydrazino-8-Methylquinoline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.