Description

2-Cyclopropaneamido-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a cyclopropaneamide and a fluorine substituent, makes it a valuable intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Precursor: Potential use in the synthesis of fluorinated polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	2-Cyclopropaneamido-5-Fluorobenzoic Acid
CAS No.	1016869-97-8
Molecular Formula	C11H10FNO3
Molecular Weight	223.20 g/mol
Synonyms	5-Fluoro-2-(cyclopropanecarboxamido)benzoic Acid; 2-(Cyclopropanecarboxamido)-5-fluorobenzoic Acid; 2-Carbamoylcyclopropane-5-fluorobenzoic Acid; Benzoic acid, 5-fluoro-2-(cyclopropanecarbonyl)amino]-; 1016869-97-8; 2-Cyclopropanecarboxamido-5-fluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Cyclopropaneamido-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.