Description

3-(Oxolan-2-Ylmethoxy)Benzonitrile is a versatile benzonitrile derivative featuring a tetrahydrofuran (oxolane) ether side chain. This compound serves as a valuable pharmaceutical intermediate and organic synthesis building block, prized for its unique molecular architecture that enables the construction of complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing novel herbicides and fungicides with specific mode-of-action profiles.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating functionalized polymers and liquid crystals with tailored electronic or optical properties.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and fluorescent tags used in biochemical assays.
• Academic & Industrial R&D: Fundamental research chemical for exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	3-(Oxolan-2-Ylmethoxy)Benzonitrile
CAS No.	1016853-20-5
Molecular Formula	C12H13NO2
Molecular Weight	203.24 g/mol
Synonyms	3-[(Tetrahydrofuran-2-yl)methoxy]benzonitrile; 3-(Tetrahydro-2-furanylmethoxy)benzonitrile; 3-((Tetrahydrofuran-2-yl)methoxy)benzonitrile; Benzonitrile, 3-[(tetrahydro-2-furanyl)methoxy]-; 3-(Oxolan-2-ylmethoxy)benzonitrile; 2-[(3-Cyanophenoxy)methyl]tetrahydrofuran; 3-(2-Tetrahydrofurylmethoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(Oxolan-2-Ylmethoxy)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. For cGMP or other regulatory-grade requirements, please contact our technical sales team to discuss available validation support and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.