Description

8-Bromo-4-Chloro-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its complex halogenated and esterified structure, which provides versatile reactive sites for constructing sophisticated heterocyclic frameworks. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, particularly for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Synthesis Scaffold: Provides a versatile core structure for further functionalization via cross-coupling reactions, hydrolysis, or amidation to create diverse chemical libraries.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-4-Chloro-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1016828-40-2
Molecular Formula	C₁₄H₁₃BrClNO₂
Molecular Weight	354.62 g/mol
Synonyms	Ethyl 8-Bromo-4-Chloro-6-Methylquinoline-3-Carboxylate; 8-Bromo-4-chloro-6-methyl-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic Acid, 8-Bromo-4-Chloro-6-Methyl-, Ethyl Ester; 1016828-40-2; 8-Br-4-Cl-6-Me-Quinoline-3-COOEt
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.