Description

4-Chloro-5,7-Difluoro-Quinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinoline core structure makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated quinoline scaffold.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline moiety into more complex molecular architectures.
• Fluorescent Probe Development: The quinoline-3-carbonitrile structure can be utilized to develop novel fluorescent dyes or sensors for biological imaging.

Basic Information

Product Name	4-Chloro-5,7-Difluoro-Quinoline-3-Carbonitrile
CAS No.	1016819-82-1
Molecular Formula	C10H3ClF2N2
Molecular Weight	224.59 g/mol
Synonyms	4-Chloro-5,7-difluoroquinoline-3-carbonitrile; 5,7-Difluoro-4-chloroquinoline-3-carbonitrile; 3-Cyano-4-chloro-5,7-difluoroquinoline; Quinoline-3-carbonitrile, 4-chloro-5,7-difluoro-; 1016819-82-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,7-Difluoro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong alkalis and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.