Description

6-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and esterified structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its halogenated quinoline core.
• Material Science Precursor: Serves as a starting material for creating functionalized organic ligands and complexes used in catalysis and electronic materials.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions, ester hydrolysis, and further functionalization to create a diverse library of specialized quinoline derivatives.
• Academic & R&D Laboratories: Utilized in medicinal chemistry programs and process research for exploring new synthetic pathways and structure-activity relationships.

Basic Information

Product Name	6-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1016780-82-7
Molecular Formula	C₁₄H₁₃BrClNO₂
Molecular Weight	342.62 g/mol
Synonyms	Ethyl 6-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylate; 6-Bromo-4-chloro-8-methyl-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic Acid, 6-Bromo-4-Chloro-8-Methyl-, Ethyl Ester; 1016780-82-7; 6-Bromo-4-chloro-8-methylquinoline-3-carboxylic acid ethyl ester; Ethyl 6-bromo-4-chloro-8-methylquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-8-Methylquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.