Description

2-(2,4-Difluorophenoxy)-3-Methylbutanoic Acid is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring a difluorophenoxy group and a branched carboxylic acid chain, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries. It serves as a critical precursor in the development of novel active ingredients, where the introduction of fluorine atoms is a key strategy to modulate bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzymes and receptors.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorinated phenoxy moiety can enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Modification: Can be incorporated as a monomer or additive to impart specific properties like chemical resistance or altered surface energy to specialty polymers.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex organic molecules, leveraging its reactive carboxylic acid and ether functionalities.
• Chemical Research Standard: Used as a reference standard or analytical reagent in quality control and method development for related compounds.

Basic Information

Product Name	2-(2,4-Difluorophenoxy)-3-Methylbutanoic Acid
CAS No.	1016734-04-5
Molecular Formula	C11H12F2O3
Molecular Weight	230.21 g/mol
Synonyms	3-Methyl-2-(2,4-difluorophenoxy)butanoic acid; 2-(2,4-Difluorophenoxy)-3-methylbutyric acid; α-(2,4-Difluorophenoxy)-isovaleric acid; DL-2-(2,4-Difluorophenoxy)-3-methylbutanoic acid; (±)-2-(2,4-Difluorophenoxy)-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenoxy)-3-Methylbutanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment. We support custom synthesis and can tailor specifications, including chiral purity, to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.