Description

Methyl 2-Methyl-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic systems due to its reactive carboxylate and quinazolinone core.
• Biochemical Research: May be utilized in the study of enzyme interactions and biochemical pathways as a tool compound.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.

Basic Information

Product Name	Methyl 2-Methyl-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylate
CAS No.	1016681-63-2
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	7-Quinazolinecarboxylic acid, 3,4-dihydro-2-methyl-4-oxo-, methyl ester; Methyl 2-methyl-4-oxo-1,4-dihydroquinazoline-7-carboxylate; 2-Methyl-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid methyl ester; 1016681-63-2; Methyl 2-methyl-4-oxoquinazoline-7-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Methyl-4-Oxo-3,4-Dihydroquinazoline-7-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.