Description

5-Methyl-2-(Thiophen-2-Yl)-1,3-Oxazole-4-Carboxylic Acid is a high-value heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines oxazole and thiophene motifs to enable the construction of complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs) due to its electron-rich thiophene unit.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.
• Dye & Pigment Intermediate: Potential use in synthesizing specialized dyes and optical materials where the oxazole-thiophene core influences color and light-absorbing properties.

Basic Information

Item	Details
Product Name	5-Methyl-2-(Thiophen-2-Yl)-1,3-Oxazole-4-Carboxylic Acid
CAS No.	1016526-89-8
Molecular Formula	C9H7NO3S
Molecular Weight	209.22 g/mol
Synonyms	5-Methyl-2-(2-thienyl)-4-oxazolecarboxylic acid; 2-(Thiophen-2-yl)-5-methyl-1,3-oxazole-4-carboxylic acid; 4-Oxazolecarboxylic acid, 5-methyl-2-(2-thienyl)-; 5-Methyl-2-thiophen-2-yl-oxazole-4-carboxylic acid; 1016526-89-8; 2-(2-Thienyl)-5-methyl-4-oxazolecarboxylic acid; 5-Methyl-2-(2-thienyl)-4-carboxyoxazole
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Thiophen-2-Yl)-1,3-Oxazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.