Description

tert-Butyl 2-(Dibromomethyl)Quinoline-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its reactive dibromomethyl and ester functional groups. This compound is of significant value for its role as a versatile building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates, particularly those targeting infectious diseases and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging the quinoline core for biological activity.
• Organic Synthesis Building Block: The reactive dibromomethyl group serves as a handle for further functionalization in multi-step synthetic routes for fine chemicals.
• Material Science Research: Employed in the development of organic semiconductors and light-emitting materials due to the conjugated quinoline structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to create complex molecular architectures.
• Academic & R&D: A valuable reagent for methodological studies and exploring new chemical transformations in academic and industrial research laboratories.

Basic Information

Product Name	tert-Butyl 2-(Dibromomethyl)Quinoline-4-Carboxylate
CAS No.	1015856-43-5
Molecular Formula	C₁₅H₁₅Br₂NO₂
Molecular Weight	401.10 g/mol
Synonyms	4-Quinolinecarboxylic acid, 2-(dibromomethyl)-, 1,1-dimethylethyl ester; 2-(Dibromomethyl)quinoline-4-carboxylic acid tert-butyl ester; tert-Butyl 2-(dibromomethyl)-4-quinolinecarboxylate; 1,1-Dimethylethyl 2-(dibromomethyl)-4-quinolinecarboxylate; TB-2-DBMQC; Quinoline-4-carboxylate dibromomethyl tert-butyl derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(Dibromomethyl)Quinoline-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.