Description

Lactose 6'-Sulfate is a chemically modified derivative of lactose, a disaccharide sugar, where a sulfate group is specifically esterified at the 6'-hydroxyl position of the galactose moiety. This targeted sulfation introduces a strong anionic charge, significantly altering its physicochemical properties and biological interactions compared to native lactose. It serves as a critical reference standard, biochemical reagent, and synthetic intermediate in advanced research and development. Key industries that utilize this specialized compound include pharmaceutical development, life science research, and specialized chemical synthesis.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity testing, and quantification of related compounds in drug development and quality control (QC/QA) laboratories.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies, particularly for sulfatases and glycosyltransferases, to investigate metabolic pathways.
• Glycobiology & Glycomics: Acts as a key building block or model compound for studying sulfated carbohydrate-protein interactions, cell signaling, and inflammation processes.
• Intermediate for Chemical Synthesis: Utilized in the synthesis of more complex sulfated oligosaccharides, glycoconjugates, or potential therapeutic agents.
• Analytical Method Development: Employed as a known compound to validate and calibrate analytical techniques such as HPLC, LC-MS, and CE for carbohydrate analysis.

Basic Information

Product Name	Lactose 6'-Sulfate
CAS No.	1015758-24-3
Molecular Formula	C12H22O14S
Molecular Weight	422.36 g/mol
Synonyms	6'-O-Sulfo-β-D-galactopyranosyl-(1→4)-D-glucopyranose; Lactose 6'-O-Sulfate; 6'-Sulfo-lactose; β-Lactose 6'-sulfate; D-Lactose 6'-sulfate; 4-O-β-D-Galactopyranosyl-6-O-sulfo-D-glucopyranose; Gal(β1-4)6S-Glc; Lactose-6'-sulfate sodium salt (common salt form)
EINECS	Contact for details

Quality Control

Our Lactose 6'-Sulfate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques such as NMR, HPLC, and MS. While produced to high-purity standards for research use, specifications can be aligned with specific project requirements. Please contact us for detailed QC protocols and batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.