Description

(S)-4-(1-Boc-Amino-Ethyl)-Benzoic Acid is a high-purity chiral building block featuring a tert-butoxycarbonyl (Boc) protected amine and a benzoic acid moiety. This compound is critical for the synthesis of complex, optically active molecules, offering precise stereochemical control in pharmaceutical development. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for creating active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for small molecule drugs.
• Peptide Mimetics & Conjugates: Used to incorporate a protected amino acid-like structure into peptide backbones or linker systems for drug delivery.
• Protease Inhibitor Synthesis: Serves as a building block for inhibitors targeting specific enzymes, leveraging its defined stereochemistry.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged molecules for studying biological pathways and target engagement.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop chiral ligands or auxiliaries for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high enantiomeric purity.

Basic Information

Product Name	(S)-4-(1-Boc-Amino-Ethyl)-Benzoic Acid
CAS No.	1014644-95-1
Molecular Formula	C₁₄H₁₉NO₄
Molecular Weight	265.31 g/mol
Synonyms	(S)-4-(1-((tert-Butoxycarbonyl)amino)ethyl)benzoic acid; (S)-4-(1-Boc-aminoethyl)benzoic acid; (S)-4-(1-(tert-Butoxycarbonylamino)ethyl)benzoic Acid; Benzoic acid, 4-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; (S)-4-(Boc-aminoethyl)benzoic acid; (S)-Boc-Aminoethylbenzoic Acid; (S)-4-(1-(Boc-amino)ethyl)benzoic acid
EINECS	Contact for details

Quality Control

Our (S)-4-(1-Boc-Amino-Ethyl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.