Description

4-Chloro-2-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block featuring a chlorinated pyrrolopyridine core substituted with a trifluoromethyl group. This compound matters for its unique structural motifs, which are critical for modulating the physicochemical and pharmacokinetic properties of advanced molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the research and synthesis of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Acts as a specialized monomer or building block for creating advanced organic electronic materials and functional polymers.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1014613-16-1
Molecular Formula	C9H4ClF3N2
Molecular Weight	232.59 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-2-(trifluoromethyl)-7-azaindole; 4-Chloro-2-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-2-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 1014613-16-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.