Description

4-Bromo-2-Methyl-1-Phenylsulfonyl-7-Azaindole is a high-purity, advanced pharmaceutical intermediate belonging to the 7-azaindole class of heterocyclic compounds. This compound matters for its critical role as a versatile building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the research and development of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Organic Synthesis Building Block: Provides a functionalized 7-azaindole core for further derivatization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Agrochemical Research: Employed in the synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	4-Bromo-2-Methyl-1-Phenylsulfonyl-7-Azaindole
CAS No.	1014613-05-8
Molecular Formula	C14H11BrN2O2S
Molecular Weight	351.22 g/mol
Synonyms	1-(Phenylsulfonyl)-4-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-2-methyl-1-tosyl-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-2-methyl-1-(phenylsulfonyl)-; 4-Br-2-Me-1-PhSO2-7-azaindole
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methyl-1-Phenylsulfonyl-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.