Description

tert-Butyl 3-Oxo-1-Phenyl-2,7-Diazaspiro[3.5]Nonane-7-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic and diazepane scaffold. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics, kinase inhibitors, and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel active pharmaceutical ingredients (APIs) targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Synthesis: Used in the construction of complex molecules designed to inhibit specific enzymes like kinases or proteases.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	tert-Butyl 3-Oxo-1-Phenyl-2,7-Diazaspiro[3.5]Nonane-7-Carboxylate
CAS No.	1014114-59-0
Molecular Formula	C18H24N2O3
Molecular Weight	316.40 g/mol
Synonyms	7-Boc-3-oxo-1-phenyl-2,7-diazaspiro[3.5]nonane; tert-Butyl 3-oxo-1-phenyl-2,7-diazaspiro[3.5]nonane-7-carboxylate; 1-Phenyl-2,7-diazaspiro[3.5]nonan-3-one 7-carboxylic acid tert-butyl ester; 2,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 3-oxo-1-phenyl-, 1,1-dimethylethyl ester; 1014114-59-0; Boc-protected diazaspiro ketone
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-Oxo-1-Phenyl-2,7-Diazaspiro[3.5]Nonane-7-Carboxylate adheres to stringent quality protocols suitable for pharmaceutical R&D and pre-clinical development. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and mass spectrometry are provided with every shipment. We support development under quality agreements and can align with ICH guidelines for stability and impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.