Description

4-Iodo-Benzo[D]Isoxazol-3-Ylamine is a high-purity, heterocyclic organic compound featuring an iodine-substituted benzoisoxazole core. This specialized chemical building block is valued for its unique reactivity and structural properties, enabling advanced synthetic pathways in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a versatile building block for synthesizing novel herbicides, fungicides, and insecticides, leveraging the iodine atom for further functionalization.
• Material Science Precursor: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its heterocyclic structure is beneficial.
• Chemical Biology Probe: Employed in the synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms due to its reactive amine and halogenated aromatic system.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl and conjugated systems.
• Ligand Synthesis: Utilized for preparing novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4-Iodo-Benzo[D]Isoxazol-3-Ylamine
CAS No.	1012367-55-3
Molecular Formula	C7H5IN2O
Molecular Weight	260.03 g/mol
Synonyms	3-Amino-4-iodo-1,2-benzisoxazole; 4-Iodo-1,2-benzisoxazol-3-amine; 4-Iodobenzo[d]isoxazol-3-amine; 4-Iodo-3-amino-1,2-benzisoxazole; 1,2-Benzisoxazole, 3-amino-4-iodo-; 3-Amino-4-iodobenzo[d]isoxazole; 4-Iodo-3-benzisoxazolamine
EINECS	Contact for details

Quality Control

Our 4-Iodo-Benzo[D]Isoxazol-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.