Description

1,1'-((2,3,5,6-Tetramethyl-1,4-Phenylene)Bis(Methylene))Bis(1H-Imidazole) is a high-purity, multi-functional organic building block characterized by its rigid, symmetrical tetramethylphenylene core flanked by two imidazole rings. This compound matters for its role as a versatile ligand and precursor in advanced material science and pharmaceutical research, offering precise structural control for complex synthesis. It is primarily needed by R&D chemists and process engineers in the fine chemical, pharmaceutical, and specialty polymer industries for developing catalysts, metal-organic frameworks (MOFs), and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Ligand for Catalysis: Used to create sophisticated transition metal complexes for asymmetric catalysis and cross-coupling reactions in fine chemical manufacturing.
• Material Science Research: Acts as a key organic linker in the construction of Metal-Organic Frameworks (MOFs) and covalent organic frameworks (COFs) for gas storage and separation.
• Polymer Modification: Employed to introduce imidazole functionality into polymer backbones, enhancing thermal stability and coordination properties.
• Agrochemical Synthesis: Utilized as an intermediate in developing advanced crop protection agents with specific modes of action.
• Academic & Industrial R&D: A valuable tool for chemists exploring new synthetic methodologies and complex molecular architectures.

Basic Information

Product Name	1,1'-((2,3,5,6-Tetramethyl-1,4-Phenylene)Bis(Methylene))Bis(1H-Imidazole)
CAS No.	1012075-54-5
Molecular Formula	C20H24N4
Molecular Weight	320.44 g/mol
Synonyms	1,1'-(2,3,5,6-Tetramethyl-1,4-phenylene)bis(methylene)bis(1H-imidazole); 1,4-Bis(imidazol-1-ylmethyl)-2,3,5,6-tetramethylbenzene; Tetramethylxylylene diimidazole; Durene-diimidazole; TMXDI (analogous to common diisocyanate abbreviation); 1,1'-(Durene-1,4-diyl)bis(methylene)bis(1H-imidazole); N,N'-(2,3,5,6-Tetramethyl-1,4-phenylene)bis(methylene)diimidazole
EINECS	Contact for details

Quality Control

Our 1,1'-((2,3,5,6-Tetramethyl-1,4-Phenylene)Bis(Methylene))Bis(1H-Imidazole) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for research and industrial use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.