Description

2H-Imidazo[4,5-C]Pyridine-2-Thione, 4-Amino-1,3-Dihydro-1-[(4-Methoxyphenyl)Methyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting specific enzyme pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing novel heterocyclic scaffolds with potential biological activity.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential new chemical entities (NCEs).
• Bioconjugation Chemistry: Potential use in developing linker molecules or probes for bioconjugation applications due to its functional groups.

Basic Information

Product Name	2H-Imidazo[4,5-C]Pyridine-2-Thione, 4-Amino-1,3-Dihydro-1-[(4-Methoxyphenyl)Methyl]-
CAS No.	1012059-50-5
Molecular Formula	C14H14N4OS
Molecular Weight	286.35 g/mol
Synonyms	4-Amino-1-[(4-methoxyphenyl)methyl]-1,3-dihydro-2H-imidazo[4,5-c]pyridine-2-thione; 1-[(4-Methoxyphenyl)methyl]-4-amino-1,3-dihydro-2H-imidazo[4,5-c]pyridine-2-thione; 4-Amino-1-(4-methoxybenzyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridine-2-thione; CAS 1012059-50-5; 2H-Imidazo[4,5-c]pyridine-2-thione, 4-amino-1,3-dihydro-1-[(4-methoxyphenyl)methyl]-; 1-(4-Methoxybenzyl)-4-amino-1,3-dihydro-2H-imidazo[4,5-c]pyridine-2-thione
EINECS	Contact for details

Quality Control

Our production of 2H-Imidazo[4,5-C]Pyridine-2-Thione, 4-Amino-1,3-Dihydro-1-[(4-Methoxyphenyl)Methyl]- adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.