Description

N,N''-[(1R,2R)-1,2-Diphenyl-1,2-Ethanediyl]Bis[N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea is a high-purity, chiral thiourea derivative designed for advanced chemical synthesis and research. This compound serves as a sophisticated organocatalyst and ligand precursor, enabling highly selective transformations critical for producing complex molecules. It is essential for researchers and manufacturers in pharmaceutical development, asymmetric synthesis, and fine chemical production who require precise stereochemical control.

Application

• Asymmetric Organocatalysis: Employed as a chiral hydrogen-bond donor catalyst for enantioselective reactions, including Michael additions and acylations.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Ligand for Metal Complexes: Acts as a precursor for creating chiral ligands used in transition metal-catalyzed reactions.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and reaction mechanisms.
• Fine Chemical Production: Facilitates the manufacture of high-value, optically pure specialty chemicals and fragrances.
• Material Science: Investigated for potential use in the development of chiral sensors or advanced polymeric materials.

Basic Information

Item	Detail
Product Name	N,N''-[(1R,2R)-1,2-Diphenyl-1,2-Ethanediyl]Bis[N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea
CAS No.	1012051-90-9
Molecular Formula	C32H22F12N4S2
Molecular Weight	754.66 g/mol
Synonyms	(1R,2R)-1,2-Diphenylethane-1,2-diyl bis(3-(3,5-bis(trifluoromethyl)phenyl)thiourea); (R,R)-Thiourea Organocatalyst; 1,2-Diphenyl-1,2-ethanediyl bis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea]; Chiral Bis(thiourea) Catalyst; N,N'-((1R,2R)-1,2-Diphenylethylene)bis(N'-(3,5-bis(trifluoromethyl)phenyl)thiourea); (R,R)-DIPH-Thiourea Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our N,N''-[(1R,2R)-1,2-Diphenyl-1,2-Ethanediyl]Bis[N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.