Description

(R)-4-Oxide-2,6-Bis[4-(4-Methoxyphenyl)--8,9,10,11,12,13,14,15-Octahydro-4-Hydroxydinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin is a sophisticated chiral organophosphorus compound characterized by its unique dinaphtho-dioxaphosphepin core structure. This compound is of significant value in advanced synthetic chemistry, particularly as a highly selective ligand or catalyst precursor for asymmetric transformations. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the synthesis of complex, optically active molecules where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for metal complexes in enantioselective hydrogenation, cross-coupling, and other C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereocontrolled construction of complex pharmacophores for new drug candidates, especially in oncology and CNS therapeutic areas.
• Advanced Material Research: Investigation into novel chiral materials for applications in nonlinear optics (NLO) or liquid crystals.
• Methodology Development: A key reagent for academic and industrial research focused on developing new catalytic asymmetric methodologies.
• Ligand Library Screening: Used in high-throughput screening to identify optimal catalytic systems for challenging synthetic transformations.

Basic Information

Product Name	(R)-4-Oxide-2,6-Bis[4-(4-Methoxyphenyl)--8,9,10,11,12,13,14,15-Octahydro-4-Hydroxydinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin
CAS No.	1011465-27-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-2,6-Bis[4-(4-Methoxyphenyl)-8,9,10,11,12,13,14,15-octahydro-4-hydroxydinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-Oxide; Chiral Dinaphtho-Dioxaphosphepin Derivative; (R)-BINAP-Diol Phosphonate Oxide Analog; CAS 1011465-27-2.
EINECS	Contact for details

Quality Control

Our high-purity specialty chemicals are manufactured under strict quality management protocols. Each batch of (R)-4-Oxide-2,6-Bis[4-(4-Methoxyphenyl)--8,9,10,11,12,13,14,15-Octahydro-4-Hydroxydinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin undergoes comprehensive analytical characterization, including HPLC for chiral purity and assay, NMR, and MS, to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.