Description

3-(5,11-Dioxoisoindolo[2,1-A]Quinazolin-6(5H,6Ah,11H)-Yl)Propanoic Acid is a high-purity, complex heterocyclic organic compound featuring a fused isoindoloquinazoline core with a propanoic acid side chain. This specialized structure makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for probing new biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new lead molecules.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for potential APIs during clinical trial material manufacturing.
• Biochemical Tool Compound: May be utilized in academic and industrial research to study enzyme inhibition or receptor-ligand interactions due to its unique fused heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client-specific research programs.

Basic Information

Product Name	3-(5,11-Dioxoisoindolo[2,1-A]Quinazolin-6(5H,6Ah,11H)-Yl)Propanoic Acid
CAS No.	1010928-60-5
Molecular Formula	C19H12N2O4
Molecular Weight	332.31 g/mol
Synonyms	3-(5,11-Dioxoisoindolo[2,1-a]quinazolin-6-yl)propanoic acid; 6-(2-Carboxyethyl)-5H,6aH,11H-isoindolo[2,1-a]quinazoline-5,11-dione; 1010928-60-5; Propanoic acid, 3-(5,11-dioxoisoindolo[2,1-a]quinazolin-6(5H,6aH,11H)-yl)-; Isoindolo[2,1-a]quinazoline-5,11-dione, 6-(2-carboxyethyl)-5,6,6a,11-tetrahydro-
EINECS	Contact for details

Quality Control

Every batch of 3-(5,11-Dioxoisoindolo[2,1-A]Quinazolin-6(5H,6Ah,11H)-Yl)Propanoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.