Description

n-(2,2-Difluoroethyl)Cyclopropanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopropylamine moiety linked to a difluoroethyl group, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclopropane and fluorine atoms can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis, leveraging the stereogenic center and amine functionality.
• Material Science Research: Employed in the synthesis of advanced polymers or functional materials where fluorinated building blocks impart specific chemical resistance or surface properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems, benefiting from the small size and potential hydrogen-bonding capability of the amine group.

Basic Information

Product Name	n-(2,2-Difluoroethyl)Cyclopropanamine
CAS No.	1010189-78-2
Molecular Formula	C5H9F2N
Molecular Weight	121.13 g/mol
Synonyms	2,2-Difluoroethylcyclopropylamine; Cyclopropanamine, N-(2,2-difluoroethyl)-; 1-Cyclopropyl-2,2-difluoroethanamine; N-(2,2-Difluoroethyl)cyclopropanamine; 2,2-Difluoro-N-cyclopropylethanamine; (2,2-Difluoroethyl)cyclopropylamine; 1-(2,2-Difluoroethyl)cyclopropanamine
EINECS	Contact for details

Quality Control

Our n-(2,2-Difluoroethyl)Cyclopropanamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our manufacturing processes are designed to meet the stringent requirements of cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.