Description

2-(6,7-Dimethoxy-Quinazolin-4-Ylamino)-Propionic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its quinazoline core structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly kinase inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key fragment in constructing complex active molecules during process development and scale-up.
• Biochemical Research: Employed as a reference standard or probe compound in biochemical assays to study enzyme inhibition and cellular pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	2-(6,7-Dimethoxy-Quinazolin-4-Ylamino)-Propionic Acid
CAS No.	1009554-30-6
Molecular Formula	C₁₃H₁₅N₃O₅
Molecular Weight	293.28 g/mol
Synonyms	2-[(6,7-Dimethoxy-4-quinazolinyl)amino]propanoic acid; 2-(6,7-Dimethoxyquinazolin-4-ylamino)propionic acid; 4-Quinazolinamine, N-(1-carboxyethyl)-6,7-dimethoxy-; 2-(6,7-Dimethoxy-quinazolin-4-ylamino)-propionic acid; 1009554-30-6; UNII-9V6S5A8V4C; 9V6S5A8V4C
EINECS	Contact for details

Quality Control

Our 2-(6,7-Dimethoxy-Quinazolin-4-Ylamino)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.