Description

5-(4-Methylbenzyl)-7-(Trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating a quinoxaline and pyrrolidine core. This compound is of significant value in medicinal chemistry research and development, particularly for its potential as a key building block in the synthesis of novel bioactive molecules. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers engaged in the discovery of new therapeutic agents, especially within neurological and oncological domains.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Biochemical Tool Compound: May be utilized in vitro to study enzyme inhibition or receptor modulation due to its distinctive chemical structure.
• Contract Research & Development (CRO): Supplied to research organizations specializing in custom synthesis and early-stage drug discovery projects.
• Academic Research: Employed in university laboratories for investigations into novel heterocyclic chemistry and its applications in life sciences.

Basic Information

Product Name	5-(4-Methylbenzyl)-7-(Trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one
CAS No.	1009537-73-8
Molecular Formula	C21H18F3N3O
Molecular Weight	385.38 g/mol
Synonyms	7-(Trifluoromethyl)-5-[(4-methylphenyl)methyl]-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4-one; 5-(4-Methylbenzyl)-7-(trifluoromethyl)-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-a]quinoxalin-4-one; CAS 1009537-73-8; Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-5-[(4-methylphenyl)methyl]-7-(trifluoromethyl)-; 5-[(4-Methylphenyl)methyl]-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one
EINECS	Contact for details

Quality Control

Our 5-(4-Methylbenzyl)-7-(Trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.