Description

5-(2,5-Dimethylbenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure, designed for demanding synthetic applications. Its core value lies in serving as a critical building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to innovate new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up and optimizing synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science applications.
• Contract Research & Manufacturing (CRMO): Supplied to organizations providing outsourced R&D and production services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-(2,5-Dimethylbenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one
CAS No.	1009409-98-6
Molecular Formula	C22H21F3N2O
Molecular Weight	386.41 g/mol
Synonyms	5-[(2,5-Dimethylphenyl)methyl]-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4-one; 7-(Trifluoromethyl)-5-(2,5-dimethylbenzyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one; Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 5-[(2,5-dimethylphenyl)methyl]-7-(trifluoromethyl)-1,2,3,3a-tetrahydro-; CAS 1009409-98-6
EINECS	Contact for details

Quality Control

Our 5-(2,5-Dimethylbenzyl)-7-(trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.