Description

4,5-Dibromonicotinic Acid is a high-purity, multi-functional brominated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications essential for developing novel active compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery and the synthesis of complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: A building block for organic electronic materials and metal-organic frameworks (MOFs) due to its functional carboxylic acid and bromine groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and specialty chemicals under cGMP conditions where required.

Basic Information

Product Name	4,5-Dibromonicotinic Acid
CAS No.	1009334-28-4
Molecular Formula	C6H3Br2NO2
Molecular Weight	280.90 g/mol
Synonyms	4,5-Dibromopyridine-3-carboxylic Acid; 3-Pyridinecarboxylic acid, 4,5-dibromo-; Nicotinic acid, 4,5-dibromo-; 4,5-Dibromo-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4,5-Dibromonicotinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with specifications that can meet research-grade through to cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.