Description

7-(Trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one is a high-value, complex heterocyclic compound featuring a fused pyrroloquinoxaline core and a strategically positioned trifluoromethyl group. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold in modern organic synthesis. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the quinoxaline moiety.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including organic semiconductors and ligands for catalysis.
• Medicinal Chemistry: A privileged scaffold for constructing compound libraries via parallel and combinatorial synthesis for high-throughput screening (HTS).
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting research in heterocyclic chemistry and fluorine chemistry.

Basic Information

Product Name	7-(Trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one
CAS No.	1009166-71-5
Molecular Formula	C₁₃H₁₁F₃N₂O
Molecular Weight	268.24 g/mol
Synonyms	7-(Trifluoromethyl)-1,2,3,3a-tetrahydro-4H-pyrrolo[1,2-a]quinoxalin-4-one; 4(5H)-Pyrrolo[1,2-a]quinoxalinone, 7-(trifluoromethyl)-1,2,3,3a-tetrahydro-; 7-Trifluoromethyl-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one; TFMPQ; 7-CF3-THPQ; 1009166-71-5
EINECS	Contact for details

Quality Control

Our production of 7-(Trifluoromethyl)-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.