Description

8-Ethyl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex polycyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of new drug candidates targeting central nervous system and other disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex APIs.
• Biochemical Research: Employed as a tool compound for studying biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	8-Ethyl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-4-Carboxylic Acid
CAS No.	1008423-48-0
Molecular Formula	C₁₅H₁₇NO₂
Molecular Weight	243.30 g/mol
Synonyms	8-Ethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid; 3H-Cyclopenta[c]quinoline-4-carboxylic acid, 8-ethyl-3a,4,5,9b-tetrahydro-; 1008423-48-0; 8-Ethyl-3a,4,5,9b-tetrahydrocyclopenta[c]quinoline-4-carboxylic acid; 8-Ethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid; 8-Ethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid (non-preferred stereochemistry).
EINECS	Contact for details

Quality Control

Our 8-Ethyl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.