Description

8-(Trifluoromethyl)-1,2,3,3A-Tetrahydropyrrolo[1,2-A]Quinoxalin-4(5H)-One is a high-value, complex heterocyclic compound featuring a fused pyrroloquinoxaline core and a strategically positioned trifluoromethyl group. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Used extensively in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection, leveraging the biological activity of the quinoxaline moiety.
• Chemical Biology Probe: Utilized as a tool compound to study biological pathways and protein-ligand interactions.
• Material Science Precursor: Investigated for the development of specialty chemicals and functional materials with unique electronic properties.

Basic Information

Product Name	8-(Trifluoromethyl)-1,2,3,3A-Tetrahydropyrrolo[1,2-A]Quinoxalin-4(5H)-One
CAS No.	1008022-69-2
Molecular Formula	C₁₃H₁₀F₃N₃O
Molecular Weight	281.24 g/mol
Synonyms	8-(Trifluoromethyl)-1,2,3,3a-tetrahydro-4H-pyrrolo[1,2-a]quinoxalin-4-one; 8-(Trifluoromethyl)-4,5-dihydro-1H-pyrrolo[1,2-a]quinoxalin-4-one; 1,2,3,3a-Tetrahydro-8-(trifluoromethyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one; 8-Trifluoromethyl-1,2,3,3a-tetrahydropyrrolo[1,2-a]quinoxalin-4(5H)-one; Pyrrolo[1,2-a]quinoxalin-4(5H)-one, 1,2,3,3a-tetrahydro-8-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 8-(Trifluoromethyl)-1,2,3,3A-Tetrahydropyrrolo[1,2-A]Quinoxalin-4(5H)-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality systems are designed to support cGMP-compliant workflows for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.