Description

Methyl 2-(5-Benzyl-4,6-Dioxo-3-Phenyloctahydropyrrolo[3,4-C]Pyrrol-1-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1008006-46-9. This compound is a critical building block in modern organic synthesis, valued for its complex pyrrolopyrrolidone core structure which serves as a key pharmacophore. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used extensively in R&D laboratories for structure-activity relationship (SAR) studies and lead optimization processes.
• Protease Inhibitor Development: Its structural motif is relevant in the design and synthesis of inhibitors for various protease enzymes.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying enzyme function and cellular signaling mechanisms.
• Custom Synthesis: A key starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.
• Academic Research: Employed in university laboratories for methodological development in heterocyclic and asymmetric synthesis.

Basic Information

Product Name	Methyl 2-(5-Benzyl-4,6-Dioxo-3-Phenyloctahydropyrrolo[3,4-C]Pyrrol-1-Yl)Acetate
CAS No.	1008006-46-9
Molecular Formula	C22H22N2O4
Molecular Weight	378.43 g/mol
Synonyms	Methyl (5-benzyl-4,6-dioxo-3-phenyloctahydro-1H-pyrrolo[3,4-c]pyrrol-1-yl)acetate; 1H-Pyrrolo[3,4-c]pyrrole-1-acetic acid, 5-(phenylmethyl)-4,6-dioxo-3-phenyloctahydro-, methyl ester; 1008006-46-9; Methyl 2-(5-benzyl-4,6-dioxo-3-phenyloctahydro-1H-pyrrolo[3,4-c]pyrrol-1-yl)acetate; (5-Benzyl-4,6-dioxo-3-phenyloctahydro-1H-pyrrolo[3,4-c]pyrrol-1-yl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(5-Benzyl-4,6-Dioxo-3-Phenyloctahydropyrrolo[3,4-C]Pyrrol-1-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and current industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.