Description

1-(Phenylsulfonyl)Cyclopropanol is a versatile organosulfur compound featuring a cyclopropanol moiety linked to a phenylsulfonyl group, serving as a valuable synthetic intermediate. Its unique structure makes it a critical building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce cyclopropane rings and sulfone functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides where the cyclopropane ring confers biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other transition metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: Fundamental reagent for methodological studies in organic chemistry, particularly in ring-opening and functional group transformation reactions.

Basic Information

Product Name	1-(Phenylsulfonyl)Cyclopropanol
CAS No.	1006613-82-6
Molecular Formula	C9H10O3S
Molecular Weight	198.24 g/mol
Synonyms	Cyclopropanol, 1-(phenylsulfonyl)-; 1-(Benzenesulfonyl)cyclopropanol; 1-(Phenylsulfonyl)cyclopropan-1-ol; (1-Hydroxycyclopropyl)(phenyl)sulfone; α-Hydroxycyclopropyl phenyl sulfone
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)Cyclopropanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.