Description

1-(tert-Butyl) 4-Ethyl 5-(Trifluoromethyl)-1H-Pyrazole-1,4-Dicarboxylate is a high-purity, multi-functional pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its trifluoromethyl group and dual carboxylate ester functionalities, which are essential for modulating the physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Building block for the research and production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Used in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials due to its versatile reactive sites.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or activity-based probes used in biochemical and cellular research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	1-(tert-Butyl) 4-Ethyl 5-(Trifluoromethyl)-1H-Pyrazole-1,4-Dicarboxylate
CAS No.	1006492-02-9
Molecular Formula	C12H15F3N2O4
Molecular Weight	308.26 g/mol
Synonyms	tert-Butyl 4-ethyl 5-(trifluoromethyl)-1H-pyrazole-1,4-dicarboxylate; 1H-Pyrazole-1,4-dicarboxylic acid, 5-(trifluoromethyl)-, 1-(1,1-dimethylethyl) 4-ethyl ester; 4-Ethyl 1-tert-butyl 5-(trifluoromethyl)-1H-pyrazole-1,4-dicarboxylate; 1-tert-Butoxycarbonyl-4-ethoxycarbonyl-5-trifluoromethylpyrazole; 1-Boc-4-COOEt-5-CF3-pyrazole
EINECS	Contact for details

Quality Control

Every batch of 1-(tert-Butyl) 4-Ethyl 5-(Trifluoromethyl)-1H-Pyrazole-1,4-Dicarboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing to ensure compliance with exacting purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.