Description

4-Bromo-1-(2,2,2-Trifluoro-Ethyl)-1H-Pyrazole-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its bromo-substituted pyrazole core and trifluoroethyl side chain. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrazole moiety.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Acts as a building block for advanced organic materials, such as liquid crystals or polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.
• Academic and Industrial R&D: Utilized in exploratory chemistry for library synthesis in drug discovery programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Bromo-1-(2,2,2-Trifluoro-Ethyl)-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1006471-09-5
Molecular Formula	C6H4BrF3N2O2
Molecular Weight	273.01 g/mol
Synonyms	4-Bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 4-bromo-1-(2,2,2-trifluoroethyl)-; 4-Bromo-1-(trifluoroethyl)pyrazole-3-carboxylic acid; 4-Bromo-1-(2,2,2-trifluoroethyl)pyrazole-3-carboxylic acid; CAS 1006471-09-5; 4-Bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1-(2,2,2-Trifluoro-Ethyl)-1H-Pyrazole-3-Carboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.