Description

3-[2-(4-Chloro-1H-Pyrazol-1-Yl)Ethyl]-2-Mercaptoquinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its unique heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers developing next-generation therapeutic agents, particularly in areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Development: Serves as a core building block in the multi-step synthesis of complex active pharmaceutical ingredients.
• Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators due to its quinazolinone and pyrazole motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	3-[2-(4-Chloro-1H-Pyrazol-1-Yl)Ethyl]-2-Mercaptoquinazolin-4(3H)-One
CAS No.	1006327-12-3
Molecular Formula	C₁₃H₁₁ClN₄OS
Molecular Weight	306.77 g/mol
Synonyms	3-[2-(4-Chloro-1H-pyrazol-1-yl)ethyl]-2-mercapto-4(3H)-quinazolinone; 2-Mercapto-3-[2-(4-chloro-1H-pyrazol-1-yl)ethyl]quinazolin-4(3H)-one; 4(3H)-Quinazolinone, 3-[2-(4-chloro-1H-pyrazol-1-yl)ethyl]-2-mercapto-; 1006327-12-3; 3-(2-(4-Chloro-1H-pyrazol-1-yl)ethyl)-2-sulfanylquinazolin-4-one; 3-(2-(4-Chloropyrazol-1-yl)ethyl)-2-mercaptoquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 3-[2-(4-Chloro-1H-Pyrazol-1-Yl)Ethyl]-2-Mercaptoquinazolin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material that meets stringent internal standards, suitable for use in GMP-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.