Description

4-(1-((tert-Butyldimethylsilyl)Oxy)-2-Methylpropan-2-Yl)Benzoic Acid is a sophisticated benzoic acid derivative featuring a tert-butyldimethylsilyl (TBDMS) protecting group, making it a critical synthetic intermediate for advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures where selective protection and deprotection of functional groups are required. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its protected functionality allows for precise molecular modifications.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for methodology development and complex molecule construction.
• Peptide & Carbohydrate Chemistry: Employed in the synthesis of modified peptides or complex sugars where temporary hydroxyl protection is necessary.
• Chemical Biology Probes: Used to create tagged or modified small molecules for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	4-(1-((tert-Butyldimethylsilyl)Oxy)-2-Methylpropan-2-Yl)Benzoic Acid
CAS No.	1005786-00-4
Molecular Formula	C₁₇H₂₈O₃Si
Molecular Weight	308.49 g/mol
Synonyms	4-(1-((tert-Butyldimethylsilyl)oxy)-2-methylpropan-2-yl)benzoic acid; 4-[1-[(tert-Butyldimethylsilyl)oxy]-2-methylpropan-2-yl]benzoic acid; 4-(2-Methyl-1-((tert-butyldimethylsilyl)oxy)propan-2-yl)benzoic acid; Benzoic acid, 4-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methyl-2-propanyl]-; 4-(1-(TBDMS-oxy)-2-methylpropan-2-yl)benzoic acid; TBDMS-protected benzoic acid derivative
EINECS	Contact for details

Quality Control

Our 4-(1-((tert-Butyldimethylsilyl)Oxy)-2-Methylpropan-2-Yl)Benzoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific research or process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.