Description

1-(Methylsulfonyl)-4-Nitro-1H-Pyrazole is a high-purity, functionalized pyrazole derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both a nitro and a methylsulfonyl group, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, ligands, and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(Methylsulfonyl)-4-Nitro-1H-Pyrazole
CAS No.	1005640-95-8
Molecular Formula	C4H5N3O4S
Molecular Weight	191.17 g/mol
Synonyms	4-Nitro-1-(methylsulfonyl)-1H-pyrazole; 1H-Pyrazole, 4-nitro-1-(methylsulfonyl)-; 1-Methylsulfonyl-4-nitropyrazole; 4-Nitro-1-methylsulfonylpyrazole; 1-(Methanesulfonyl)-4-nitro-1H-pyrazole; 4-Nitro-1-(methanesulfonyl)pyrazole; 1-Mesyl-4-nitro-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-(Methylsulfonyl)-4-Nitro-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.