Description

3-Methyl-5-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, distinguished by its trifluoromethoxy and methyl substituents. This compound is prized for its role as a versatile synthetic intermediate, offering unique electronic and steric properties that are critical in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a core structure for developing advanced electronic materials and functional dyes.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination chemistry and creating specialized chemical libraries.
• Peptide Mimetics & Bio-conjugation: The carboxylic acid functionality allows for its use in constructing peptide analogs and linker molecules for bioconjugation.

Basic Information

Product Name	3-Methyl-5-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1005378-68-6
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	(E)-3-[3-Methyl-5-(trifluoromethoxy)phenyl]acrylic acid; 3-(3-Methyl-5-(trifluoromethoxy)phenyl)-2-propenoic acid; 3-Methyl-5-(trifluoromethoxy)cinnamate; 3-Methyl-5-trifluoromethoxycinnamic Acid; 5-(Trifluoromethoxy)-3-methylcinnamic Acid; (2E)-3-[3-Methyl-5-(trifluoromethoxy)phenyl]prop-2-enoic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(Trifluoromethoxy)Cinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.