Description

8-Fluoro-4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1005243-69-5. This structurally complex heterocyclic compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for central nervous system (CNS) and oncology targets.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways.

• Pharmaceutical Research & Development: A crucial scaffold for synthesizing novel drug candidates targeting various disease pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step production of complex final drug molecules.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Contract Research Organizations (CROs) & CDMOs: Sourced for custom synthesis projects and process development for client molecules.
• Biochemical Research: Potential use as a tool compound or probe in biological assay development and target validation.

Basic Information

Product Name	8-Fluoro-4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline
CAS No.	1005243-69-5
Molecular Formula	C17H13FN2
Molecular Weight	264.30 g/mol
Synonyms	8-Fluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 8-fluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-; 1005243-69-5; 8-Fluoro-4-(3-pyridyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4-Pyridin-3-Yl-3A,4,5,9B-Tetrahydro-3H-Cyclopenta[C]Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. All batches are analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.