Description

(4R)-3-[(2R,3S)-3-Hydroxy-1-Oxo-2-(2-Propen-1-Yl)-4-Penten-1-Yl]-4-(Phenylmethyl)-2-Oxazolidinone is a high-purity chiral oxazolidinone derivative, a critical building block in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and intermediate for constructing complex, stereochemically defined molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Chiral Auxiliary: Used in stereoselective organic synthesis to control the stereochemistry of new carbon-carbon and carbon-heteroatom bond formations.
• Fine Chemical Synthesis: Employed in the research and production of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Agrochemical Development: Serves as a building block for creating novel, stereospecific pesticides and herbicides.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and catalysis studies.
• Process Chemistry: Used in scaling up synthetic routes for commercial production where stereochemical integrity is paramount.

Basic Information

Product Name	(4R)-3-[(2R,3S)-3-Hydroxy-1-Oxo-2-(2-Propen-1-Yl)-4-Penten-1-Yl]-4-(Phenylmethyl)-2-Oxazolidinone
CAS No.	1005006-69-8
Molecular Formula	C18H21NO4
Molecular Weight	315.36 g/mol
Synonyms	(4R)-4-Benzyl-3-[(2R,3S)-3-hydroxy-1-oxo-2-(prop-2-en-1-yl)pent-4-en-1-yl]oxazolidin-2-one; (4R)-4-Benzyl-3-[(2R,3S)-3-hydroxy-1-oxo-2-(2-propenyl)-4-pentenyl]-2-oxazolidinone; Evans Auxiliary Derivative; Chiral Oxazolidinone Auxiliary; (R)-4-Benzyl-3-[(2R,3S)-3-hydroxy-1-oxo-2-allylpent-4-enoyl]oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (4R)-3-[(2R,3S)-3-Hydroxy-1-Oxo-2-(2-Propen-1-Yl)-4-Penten-1-Yl]-4-(Phenylmethyl)-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.