Description

1-Ethyl-3-(Trifluoromethyl)-1H-Pyrazole-5-Carbohydrazide is a specialized heterocyclic building block featuring a carbohydrazide functional group. This compound is of significant value in advanced organic synthesis, particularly for the construction of complex molecules with tailored biological activities. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in medicinal chemistry and crop protection agent discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generations of herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole and trifluoromethyl groups.
• Chemical Biology Probe Synthesis: Used to create molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity advanced intermediates.

Basic Information

Product Name	1-Ethyl-3-(Trifluoromethyl)-1H-Pyrazole-5-Carbohydrazide
CAS No.	1004643-69-9
Molecular Formula	C7H9F3N4O
Molecular Weight	222.17 g/mol
Synonyms	1-Ethyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid hydrazide; 5-Hydrazinylcarbonyl-1-ethyl-3-(trifluoromethyl)pyrazole; 1-Ethyl-3-trifluoromethyl-1H-pyrazole-5-carbohydrazide; 1H-Pyrazole-5-carbohydrazide, 1-ethyl-3-(trifluoromethyl)-; 1-Ethyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic hydrazide; 1-Ethyl-3-(trifluoromethyl)pyrazole-5-carbohydrazide
EINECS	Contact for details

Quality Control

Every batch of 1-Ethyl-3-(Trifluoromethyl)-1H-Pyrazole-5-Carbohydrazide undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing results for assay, purity (HPLC), and identification is provided with each shipment to support your quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.