Description

([(4-Chloro-1H-Pyrazol-1-Yl)Methyl]Thio)Acetic Acid is a high-purity, specialized organic building block featuring a unique heterocyclic pyrazole core functionalized with chloro, methylthio, and acetic acid groups. This compound matters as a versatile and critical intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, enabling the development of next-generation products. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block for creating novel herbicides, fungicides, and insecticides with potential new modes of action.
• Ligand and Catalyst Development: Used in organometallic chemistry to develop new chelating ligands and catalysts for asymmetric synthesis.
• Material Science Research: A precursor for synthesizing functional polymers or organic electronic materials with specific properties.
• Bioconjugation Chemistry: Potential use in developing linkers for antibody-drug conjugates (ADCs) or other bioconjugation strategies due to its reactive handles.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CMOs for custom synthesis projects requiring this specific molecular scaffold.

Basic Information

Product Name	([(4-Chloro-1H-Pyrazol-1-Yl)Methyl]Thio)Acetic Acid
CAS No.	1004643-61-1
Molecular Formula	C7H7ClN2O2S
Molecular Weight	218.66 g/mol
Synonyms	2-[[(4-Chloro-1H-pyrazol-1-yl)methyl]thio]acetic Acid; (4-Chloro-1H-pyrazol-1-yl)methanethiol Acetic Acid Ester; 1-[(Carboxymethyl)thio]methyl-4-chloro-1H-pyrazole; Acetic Acid, [(4-Chloro-1H-pyrazol-1-yl)methyl]thio]-; 1004643-61-1
EINECS	Contact for details

Quality Control

Our ([(4-Chloro-1H-Pyrazol-1-Yl)Methyl]Thio)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.