Description

4-(2,3-Difluorophenyl)Piperidine Hydrochloride (Wxfc0633S1) is a high-purity, fluorinated piperidine derivative, serving as a critical building block in modern pharmaceutical research and development. Its core value lies in enabling the synthesis of novel, complex molecules, particularly for central nervous system (CNS) and other therapeutic targets. This advanced intermediate is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to accelerate drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), especially in CNS drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated aromatic and piperidine motifs.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Ligand and Receptor Studies: Employed in the synthesis of compounds for probing biological targets such as enzymes, receptors, and ion channels.
• Library Synthesis: A valuable component for creating diverse compound libraries in high-throughput screening (HTS) campaigns.
• Agrochemical Research: Potential application in the synthesis of novel crop protection agents and pesticides.

Basic Information

Product Name	4-(2,3-Difluorophenyl)Piperidine Hydrochloride (Wxfc0633S1)
CAS No.	1004618-90-9
Molecular Formula	C11H13F2N·HCl
Molecular Weight	233.69 g/mol (Free base)
Synonyms	4-(2,3-Difluorophenyl)piperidine HCl; 4-(2,3-Difluorophenyl)piperidine hydrochloride; 1-(2,3-Difluorophenyl)-4-piperidinyl hydrochloride; Piperidine, 4-(2,3-difluorophenyl)-, hydrochloride (1:1); Wxfc0633S1
EINECS	Contact for details

Quality Control

Our 4-(2,3-Difluorophenyl)Piperidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.